N-Boc-4-哌啶乙醇合成路线 (共 41 条)
反应条件
in N,N-dimethyl-formamide
参考文献
US6265434 B1, ;
US 6265434 B1
参考文献
US6140333 A1, ;
US 6140333 A
反应条件
1: H2 / 5percent PtO2 / acetic acid 2: 95 percent / NaOH / dioxane 3: 91 percent / BH3*THF View Scheme
参考文献
Tetrahedron Letters, , vol. 36, # 41 p. 7379 - 7382
反应条件
1: 95 percent / NaOH / dioxane 2: 91 percent / BH3*THF View Scheme
参考文献
Tetrahedron Letters, , vol. 36, # 41 p. 7379 - 7382
参考文献
US2003/187016 A1, ;
US 20030187016 A1
反应条件
1: With hydrogen; 10-20 palladium hydroxide on carbon 2: With lithium hydroxide 3: With dimethylsulfide borane complex
参考文献
US2004/2504 A1, ;
Page/Page column 23-24; 26-27 ;
US 20040002504 A1
反应条件
1: 1.) oxalyl chloride, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 20 min, 2.) CH2Cl2, from -78 deg C to RT, 1.5 h 2: CH2Cl2 / Ambient temperature View Scheme
参考文献
Egbertson, Melissa S.; Chang, Charles T.-C.; Duggan, Mark E.; Gould, Robert J.; Halczenko, Wasyl; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 16 p. 2537 - 2551
反应条件
triethylamine in chloroform T=20°C;
参考文献
MYRIAD GENETICS, INC.
Patent: WO2009/65035 A1, 2009 ;
Location in patent: Page/Page column 141-142 ;