(3-溴丙氧基)-叔丁基二甲基硅烷合成路线 （共 12 条）
反应条件
1H-imidazole in N,N-dimethyl-formamide T=20°C; 1.5 h;
参考文献
Christiansen, Michael A.; Andrus, Merritt B.
Tetrahedron Letters, 2012 , vol. 53, # 36 p. 4805 - 4808
反应条件
1: 3-bromopropan-1-ol With 2,6-dimethylpyridine; CaH2 in dichloromethane T=0°C; Inert atmosphere; 2: t-butyldimethylsiyl triflate in dichloromethane T=20°C; 2 h; Inert atmosphere;
参考文献
Kong, Biao; Tang, Jing; Wu, Zhangxiong; Wei, Jing; Wu, Hao; Wang, Yongcheng; Zheng, Gengfeng; Zhao, Dongyuan
Angewandte Chemie - International Edition, 2014 , vol. 53, # 11 p. 2988 - 2992
Angew. Chem., 2014 , vol. 53, # 11 p. 3
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane T=25°C; 3 h;
参考文献
Fournier-Nguefack, Christelle; Lhoste, Paul; Sinou, Denis
Journal of Chemical Research, Miniprint, 1998 , # 3 p. 614 - 634
反应条件
in N-methyl-acetamide
反应条件
in tetrahydrofuran; ethyl acetate
反应条件
1: 91 percent / 16 h / 60 °C 2: 85 percent / CH2Cl2; various solvent(s) / 4 h / 0 °C View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 66, p. 1794 - 1804
反应条件
1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) in acetonitrile T=150°C; 0.0833333 h; Microwave irradiation;
参考文献
Shah, Syed Tasadaque A.; Guiry, Patrick J.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 12 p. 2168 - 2172
反应条件
1: With potassium carbonate in acetontrile T=50°C; 2: With water in acetonitrile
参考文献
US2007/32478 A1, ;
Page/Page column 89 ;
US 20070032478 A1
反应条件
1: piperidin-2-one With sodium hydride in tetrahydrofuran
T=20°C; 3 h;
2: 3-(tert-butyldimethylsilyloxy)-1-bromopropane in tetrahydrofuran; N,N-dimethyl-formamide
T=20°C; 96 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1640366 A1, 2006 ;
Location in patent: Page/Page column 31 ;
