T=200°C; im Autoklaven; d-pulegone;

T=70°C; Hydrogenation;

Hydrogenation; d-pulegone;

暂无反应条件数据

1.1: lithium diisopropyl amide 2.1: tris-(dibenzylideneacetone)dipalladium(0); di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine; potassium carbonate 3.1: lithium diisopropyl amide / -25 °C 4.1: sodium tetrahydroborate 5.1: triethylamine; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl acetamide / 130 °C 6.1: 4-methylmorpholine N-oxide; tetrapropylammonium perruthennate 7.1: tetrahydrofuran / 3 h / -25 °C / |Inert atmosphere 8.1: borane-THF; sodium hydroxide; dihydrogen peroxide / tetrahydrofuran / 3 h / 0 - 20 °C / |Inert atmosphere 9.1: triethylamine; methanesulfonyl chloride / dichloromethane / 20 °C / |Inert atmosphere 9.2: 0.5 h / 20 °C / |Inert atmosphere 9.3: 3 h / |Inert atmosphere 10.1: thionyl chloride / N,N-dimethyl acetamide / 9 h / 20 °C / |Inert atmosphere 11.1: hydrogen bromide / water / 10 h / |Reflux 12.1: palladium 10 on activated carbon; hydrogen / ethanol / 12 h / 20 °C View Scheme

dihydrogen peroxide; sodium ethanolate in ethanol; water; acetone T=0°C;

Chlorella vulgaris 24 h; Culture medium;

titanium tetrachloride; magnesium; tert-butyl alcohol in tetrahydrofuran 48 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

NADH-H+; Triton X-100 T=30°C; 24 h; Na-Pi-buffer, reductase II from nicotiana tabacum cell cultures; Yield given;

Nicotiana tabacum cells in water T=25°C; 96 h; biotransformation;