反应条件
1: 2-chloro-thiazole; tri-isopropoxy-borane With n-butyllithium; diisopropylamine in diethyl ether; toluene
T=-90 - 20°C; 3 h;
2: 2,3-dimethylbutane-2,3-diol in diethyl ether; toluene
T=20°C; 0.25 h;
3: With acetic acid in diethyl ether; toluene
参考文献
Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael
Patent: US2011/230462 A1, 2011 ;
Location in patent: Page/Page column 112-113 ;
US 20110230462 A1