4-(叔丁基磺酰基)苯甲醛合成路线 （共 11 条）
反应条件
potassium carbonate in dimethyl sulfoxide T=100°C; 3 h;
参考文献
The Research Foundation of State University of New York
Patent: US7449578 B1, 2008 ;
Location in patent: Page/Page column 6 ;
反应条件
1: 4-(tert-butylsulfanyl)bromobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.25 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; water T=20°C; 0.5 h;
参考文献
Stuhr-Hansen, Nicolai; Christensen, Jorn B.; Harrit, Niels; Bjornholm, Thomas
Journal of Organic Chemistry, 2003 , vol. 68, # 4 p. 1275 - 1282
反应条件
anhydrous iron chloride; caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=135°C; 24 h; Inert atmosphere;
参考文献
Wu, Jhih-Ru; Lin, Che-Hung; Lee, Chin-Fa
Chemical Communications, 2009 , # 29 p. 4450 - 4452
反应条件
caesium carbonate in dimethyl sulfoxide T=25°C; 0.75 h;
参考文献
Kondoh, Azusa; Yorimitsu, Hideki; Oshima, Koichiro
Tetrahedron, 2006 , vol. 62, # 10 p. 2357 - 2360
反应条件
1: 4-chlorobenzaldehyde With palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide T=20°C; 0.0833333 h; Inert atmosphere; 2: (t-BuS)3In With caesium carbonate in N,N-dimethyl-formamide T=100°C; 4 h; Inert atmosphere;
参考文献
Atobe, Shingo; Sonoda, Motohiro; Suzuki, Yuki; Shinohara, Hiroyuki; Yamamoto, Takuya; Ogawa, Akiya
Chemistry Letters, 2011 , vol. 40, # 9 p. 980 - 982
反应条件
in various solvent(s) T=20°C; 20 h;
参考文献
Grunder, Sergio; Huber, Roman; Horhoiu, Viviana; Gonzalez, Maria Teresa; Schoenenberger, Christian; Calame, Michel; Mayor, Marcel
Journal of Organic Chemistry, 2007 , vol. 72, # 22 p. 8337 - 8344
反应条件
1.1: 82 percent / aluminium chloride / 0.5 h / 20 °C 2.1: butyllithium / hexane; tetrahydrofuran / -40 °C 2.2: 82 percent / hexane; tetrahydrofuran / -78 - 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 42 p. 13720 - 13726
反应条件
palladium diacetate; N-ethyl-N,N-diisopropylamine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide T=90°C; 2 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 73, # 18 p. 7413 - 7416
反应条件
1: toluene-4-sulfonic acid / toluene / 98 °C 2: DMI / 150 °C 3: hydrogenchloride / 1,4-dioxane / 20 °C View Scheme
参考文献
Chimia, , vol. 64, # 3 p. 140 - 144
反应条件
potassium fluoride; dimethylammonium chloride in ethanol
Henry reaction; 18 h; Reflux;
参考文献
Cloonan, Suzanne M.; Keating, John J.; Butler, Stephen G.; Knox, Andrew J.S.; Jorgensen, Anne M.; Peters, Guenther H.; Rai, Dilip; Corrigan, Desmond; Lloyd, David G.; Williams, D. Clive; Meegan, Mary J.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 12 p. 4862 - 4888
