4-溴-1-三苯甲基-1H-咪唑合成路线 （共 6 条）
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=20°C; 20 h; Yields of byproduct given;
参考文献
Palmer, Brian D.; Denny, William A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 95 - 99
反应条件
triethylamine in chloroform T=20°C; Cooling with ice;
参考文献
Roumen, Luc; Peeters, Joris W.; Emmen, Judith M. A.; Beugels, Ilona P. E.; Custers, Erica M. G.; De Gooyer, Marcel; Plate, Ralf; Pieterse, Koen; Hilbers, Peter A. J.; Smits, Jos F. M.; Vekemans, Jef A. J.; Leysen, Dirk; Ottenheijm, Harry C. J.; Janssen, Henk M.; Rob Hermans
Journal of Medicinal Chemistry, 2010 , vol. 53, # 4 p. 1712 - 1725
反应条件
triethylamine in dichloromethane T=20°C; 20 h;
参考文献
Palmer, Brian D.; Denny, William A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 95 - 99
反应条件
hydrogenchloride; n-butyllithium; n-propyl nitrate 1) hexane, THF, 0 deg C, 1 h; 2) 20 deg C, 2 h; 3) MeOH; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 95 - 99
反应条件
n-butyllithium 1) hexane, O deg C, 45 min;, 2) 20 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Palmer, Brian D.; Denny, William A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 95 - 99
反应条件
hydrogenchloride; n-butyllithium; n-propyl nitrate 1) hexane, THF, 0 deg C, 1 h; 2) 20 deg C, 2 h; 3) MeOH; Yield given. Multistep reaction;
参考文献
Palmer, Brian D.; Denny, William A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 95 - 99
