3-甲氧基-3-苯基-2-哌啶酮合成路线 （共 6 条）
反应条件
hydrogen; acetic acid; platinum(IV) oxide
P=2430.6 Torr; 7 h;
参考文献
Brouillette; Grunewald
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 202 - 206
反应条件
1: 53 percent / 20percent aq. HCl / ethanol / 1 h / Heating
2: 1.) NaH / 1.) DME, RT, 30 min, 2.) DME, reflux, 1 h
3: 72 percent / H2, glacial AcOH / PtO2 / 7 h / 2430.6 Torr
View Scheme
参考文献
Brouillette; Grunewald
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 202 - 206
反应条件
1: 1.) NaH / 1.) DME, 2.) DME, RT, overnight
2: 72 percent / H2, glacial AcOH / PtO2 / 7 h / 2430.6 Torr
View Scheme
参考文献
Brouillette; Grunewald
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 202 - 206
反应条件
1: 1.) NaH / 1.) DME, RT, 30 min, 2.) DME, reflux, 1 h
2: 72 percent / H2, glacial AcOH / PtO2 / 7 h / 2430.6 Torr
View Scheme
参考文献
Brouillette; Grunewald
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 202 - 206
反应条件
1: 1.) NaH / 1.) DME, 2.) DME, RT, 2 h
2: 1.) NaH / 1.) DME, 2.) DME, RT, overnight
3: 72 percent / H2, glacial AcOH / PtO2 / 7 h / 2430.6 Torr
View Scheme
参考文献
Brouillette; Grunewald
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 202 - 206
反应条件
in toluene
7 h; Heating;
参考文献
Brouillette; Grunewald
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 202 - 206
