N-(羟基甲基)-N-甲基苯甲酰胺合成路线 （共 10 条）
反应条件
sodium perchlorate in water; acetonitrile
controlled-potential electrolysis; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Hall, Larry R.; Iwamoto, Reynold T.; Hanzlik, Robert P.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2446 - 2451
反应条件
1: 84 percent / 2M aq. NaOH / tetrahydrofuran / 6 h / 25 °C
2: NaClO4 / acetonitrile; H2O / controlled-potential electrolysis
View Scheme
参考文献
Hall, Larry R.; Iwamoto, Reynold T.; Hanzlik, Robert P.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2446 - 2451
反应条件
water in acetonitrile
T=25°C; Rate constant;
参考文献
Iley, Jim; Moreira, Rui; Rosa, Eduarda
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1991 , # 5 p. 563 - 570
反应条件
water in acetonitrile
T=37°C; Kinetics;
参考文献
Iley, Jim; Moreira, Rui; Calheiros, Teresa; Mendes, Eduarda
Pharmaceutical Research, 1997 , vol. 14, # 11 p. 1634 - 1639
反应条件
water in acetonitrile
T=37°C; Kinetics;
参考文献
Iley, Jim; Moreira, Rui; Calheiros, Teresa; Mendes, Eduarda
Pharmaceutical Research, 1997 , vol. 14, # 11 p. 1634 - 1639
反应条件
phosphate buffer in acetonitrile
T=20°C; pH=7.4; KineticsProduct distribution;
参考文献
Moreira, Rui; Calheiros, Teresa; Cabrita, Jose; Mendes, Eduarda; Pimentel, Madalena; Iley, Jim
Pharmaceutical Research, 1996 , vol. 13, # 1 p. 70 - 75
反应条件
aq. buffer in acetonitrile
T=20°C; KineticsProduct distribution; Further Variations:pH-values;
参考文献
Moreira, Rui; Calheiros, Teresa; Cabrita, Jose; Mendes, Eduarda; Pimentel, Madalena; Iley, Jim
Pharmaceutical Research, 1996 , vol. 13, # 1 p. 70 - 75
反应条件
phosphate buffer in acetonitrile
T=20°C; pH=7.4; 10 h; KineticsProduct distribution; Further Variations:pH-values;
参考文献
Moreira, Rui; Calheiros, Teresa; Cabrita, Jose; Mendes, Eduarda; Pimentel, Madalena; Iley, Jim
Pharmaceutical Research, 1996 , vol. 13, # 1 p. 70 - 75
反应条件
1: t-BuOOH; 5,10,15,20-tetraphenylporphyrinatoiron(III) chloride / CH2Cl2 / 30 °C
2: chlorotrimethylsilane / 18 h / Heating
3: tetrahydrofuran / 12 h
4: t-BuOOH; 5,10,15,20-tetraphenylporphyrinatoiron(III) chloride / CH2Cl2 / 30 °C
View Scheme
参考文献
Constantino, Luis; Iley, Jim
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 13 p. 1894 - 1900
反应条件
tert.-butylhydroperoxide; 5,10,15,20-tetrakisphenylporphyrinatoiron(III) chloride in dichloromethane
T=30°C;
参考文献
Constantino, Luis; Iley, Jim
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 13 p. 1894 - 1900
