3-苄氧基-2-羟基苯甲醛合成路线 （共 12 条）
反应条件
1: With bromine; magnesium in diethyl ether; benzene
T=0 - 20°C; Heating / reflux;
2: With hydrogenchloride in water
0.5 h; Heating / reflux;
参考文献
PLEXXIKON, INC.
Patent: WO2008/80001 A2, 2008 ;
Location in patent: Page/Page column 87 ;
反应条件
1: 2,3-dihydroxy-benzaldehyde With sodium hydride in tetrahydrofuran
T=20°C; 1 h;
2: benzyl bromide in tetrahydrofuran
24 h;
参考文献
Wrona, Iwona E.; Gozman, Alexander; Taldone, Tony; Chiosis, Gabriela; Panek, James S.
Journal of Organic Chemistry, 2010 , vol. 75, # 9 p. 2820 - 2835
反应条件
sodium hydride in dimethyl sulfoxide
T=25°C; 17 h; NaH : pyrocatechlol 2.2; Yields of byproduct given;
参考文献
Kessar, Satinder V.; Gupta, Yash P.; Mohammad, Taj; Goyal, Manju; Sawal, Kewal K.
Journal of the Chemical Society, Chemical Communications, 1983 , # 7 p. 400 - 401
反应条件
cerium(III) chloride; sodium iodide in acetonitrile
dealkylation; 10 h; Heating;
参考文献
Yadav; Subba Reddy; Madan; Riaz Hashim
Chemistry Letters, 2000 , # 7 p. 738 - 739
反应条件
sodium hydride in dimethyl sulfoxide
参考文献
Kessar, Satinder Vir; Gupta, Yash Pal; Mohammad, Taj; Khurana, Achla; Sawal, Kewal Krishan
Heterocycles, 1984 , vol. 22, # 12 p. 2723 - 2724
反应条件
1: potassium carbonate / acetone / 8 h / |Reflux
2: sodium hydroxide / water / 4 h / |Reflux
View Scheme
参考文献
Liu, Wen-Jing; Mei, De-Sheng; Duan, Wen-Hu
Chinese Chemical Letters, 2013 , vol. 24, # 6 p. 515 - 517
反应条件
1: potassium carbonate / acetone / 8 h / |Reflux
2: sodium hydroxide / water / 4 h / |Reflux
View Scheme
参考文献
Liu, Wen-Jing; Mei, De-Sheng; Duan, Wen-Hu
Chinese Chemical Letters, 2013 , vol. 24, # 6 p. 515 - 517
反应条件
sodium hydroxide in water
Reimer-Tiemann Phenol Formylation; 4 h; Reflux;
参考文献
Liu, Wen-Jing; Mei, De-Sheng; Duan, Wen-Hu
Chinese Chemical Letters, 2013 , vol. 24, # 6 p. 515 - 517
反应条件
bromine; sodium acetate in acetic acid
T=25°C; 2 h;
参考文献
Nicolaou; Sasmal, Pradip K.; Xu, Hao
Journal of the American Chemical Society, 2004 , vol. 126, # 17 p. 5493 - 5501
反应条件
triethylamine in benzene
2 h;
参考文献
Kessar, Satinder V.; Gupta, Yash P.; Balakrishnan, Prasanna; Sawal, Kewal K.; Mohammad, Taj; Dutt, Mahesh
Journal of Organic Chemistry, 1988 , vol. 53, # 8 p. 1708 - 1713
