1: in tetrahydrofuran T=0°C; 0.25 h; 2: With triethylamine in tetrahydrofuran T=0 - 20°C; 3 h;

1.1: 18.0 g / HCl / H2O; tetrahydrofuran / 2 h / Heating 2.1: tetrahydrofuran / 0.25 h / 0 °C 2.2: 67 percent / triethylamine / tetrahydrofuran / 3 h / 0 - 20 °C View Scheme

1.1: sodium hydride / tetrahydrofuran / 0 - 20 °C 2.1: 18.0 g / HCl / H2O; tetrahydrofuran / 2 h / Heating 3.1: tetrahydrofuran / 0.25 h / 0 °C 3.2: 67 percent / triethylamine / tetrahydrofuran / 3 h / 0 - 20 °C View Scheme