1H-吡咯并[2,3-B]吡啶-5-羧酸乙酯合成路线 （共 3 条）
反应条件
triethylamine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; palladium dichloride
T=120°C; P=30003 Torr; Product distribution / selectivity;
参考文献
EISAI LONDON RESEARCH LABORATORIES LIMITED
Patent: WO2005/85244 A1, 2005 ;
Location in patent: Page/Page column 46-48 ;
WO 2005/085244 A1
反应条件
1: With sulfuric acid
Heating / reflux;
2: With sodium hydrogencarbonate in ethanol; water; ethyl acetate
Product distribution / selectivity;
参考文献
EISAI LONDON RESEARCH LABORATORIES LIMITED
Patent: WO2005/85244 A1, 2005 ;
Location in patent: Page/Page column 46-47 ;
WO 2005/085244 A1
反应条件
potassium hydroxide; iodine in DMF (N,N-dimethyl-formamide)
0.583333 h;
参考文献
EISAI LONDON RESEARCH LABORATORIES LIMITED
Patent: WO2005/85244 A1, 2005 ;
Location in patent: Page/Page column 46; 48-49 ;
WO 2005/085244 A1
