2,4-二氯-5-氟苯酰氯合成路线 （共 21 条）
参考文献
Rohm and Haas Company
Patent: US5886210 A1, 1999 ;
参考文献
ROHM AND HAAS COMPANY
Patent: EP825173 A1, 1998 ;
参考文献
Zheng, Xiumian; Li, Zhong; Wang, Yanli; Chen, Weidong; Huang, Qingchun; Liu, Chuanxiang; Song, Gonghua
Journal of Fluorine Chemistry, 2003 , vol. 123, # 2 p. 163 - 169
反应条件
pyridine in 1,4-dioxane 1.) 2 h, room temperature, 2.) 1 h, 70 - 80 deg C.;
参考文献
Grohe, Klaus; Heitzer, Helmut
Liebigs Annalen der Chemie, 1987 , p. 29 - 37
反应条件
1: 54 percent / pyridine / dioxane / 1.) 2 h, room temperature, 2.) 1 h, 70 - 80 deg C.
2: 74 percent / potassium t-butylate / dioxane / 1.) 30 min, room temperature, 2.) 2 h, reflux
View Scheme
参考文献
Grohe, Klaus; Heitzer, Helmut
Liebigs Annalen der Chemie, 1987 , p. 29 - 37
反应条件
magnesium in tetrachloromethane; ice-water; ethanol
参考文献
Bayer Aktiengesellschaft
Patent: US4563459 A1, 1986 ;
反应条件
tetrachloromethane; ethanol; magnesium in ethanol; toluene
1.) 0 to -5 deg C, 2.) 12 h, room temperature; Yield given;
参考文献
Grohe, Klaus; Heitzer, Helmut
Liebigs Annalen der Chemie, 1987 , p. 29 - 37
反应条件
1: Mg/ethanol, CCl4 / ethanol; toluene / 1.) 0 to -5 deg C, 2.) 12 h, room temperature
2: p-toluenesulfonic acid / H2O / 5 h / Heating
3: acetic anhydride / 2 h / Heating
View Scheme
参考文献
Grohe, Klaus; Heitzer, Helmut
Liebigs Annalen der Chemie, 1987 , p. 29 - 37
反应条件
1: Mg/ethanol, CCl4 / ethanol; toluene / 1.) 0 to -5 deg C, 2.) 12 h, room temperature
2: p-toluenesulfonic acid / H2O / 5 h / Heating
3: acetic anhydride / 2 h / Heating
4: 92 percent / ethanol / 1 h / Ambient temperature
View Scheme
参考文献
Grohe, Klaus; Heitzer, Helmut
Liebigs Annalen der Chemie, 1987 , p. 29 - 37
反应条件
potassium carbonate; acetic acid; triethylamine in water; chlorobenzene; isopropyl alcohol
参考文献
Bayer Aktiengesellschaft
Patent: US6229017 B1, 2001 ;
