3,4,5-三甲氧基苯甲醛合成路线 （共 427 条）
反应条件
in ethanol; acetic acid
参考文献
Popp
Journal of Pharmaceutical Sciences, 1973 , vol. 62, # 4 p. 679 - 680
反应条件
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / 0 °C
1.2: 6 h / 0 - 25 °C
2.1: hydrogenchloride / acetone; water / 25 °C
View Scheme
参考文献
Haridas, K.; Dev, Sukh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1018 - 1020
反应条件
piperidine; acetic acid in toluene
12 h; Reflux;
参考文献
Chen, Huan; Li, Yongmei; Sheng, Chunquan; Lv, Zhiliang; Dong, Guoqiang; Wang, Tiantian; Liu, Jia; Zhang, Mingfeng; Li, Lingzhen; Zhang, Tao; Geng, Dongping; Niu, Chunjuan; Li, Ke
Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 685 - 699
反应条件
1: (i) Et2O, (ii) CrO3, aq. H2SO4, acetone
2: Br2 / CHCl3
View Scheme
参考文献
Barata,L.E.S. et al.
Phytochemistry (Elsevier), 1978 , vol. 17, p. 783 - 786
反应条件
1: 83 percent / dimethylammonium chloride, KF / toluene / 5 h / Heating
2: 92.5 percent / silicagel (200-400 mesh ASTM), NaBH4 / propan-2-ol; CHCl3 / 2 h
View Scheme
参考文献
Dauzonne; Royer
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1628 - 1633
反应条件
in dichloromethane
0.5 h; Ambient temperature;
参考文献
Bestmann, Hans Juergen; Frey, Herbert
Liebigs Annalen der Chemie, 1980 , # 12 p. 2061 - 2071
反应条件
tris(methoxyethoxyethyl)amine; potassium carbonate in dichloromethane; water
T=40°C; 18 h; Rate constant;
参考文献
Daubresse, Nicolas; Francesch, Charlette; Rolando, Christian
Tetrahedron, 1998 , vol. 54, # 36 p. 10761 - 10770
