6,9-二氯-2-甲氧基吖啶合成路线 （共 38 条）
反应条件
1: With trichlorophosphate T=130°C; 3 h; 2: With ammonia in chloroform; water Cooling with ice;
参考文献
Lang, Xu-Liang; Sun, Qin-Sheng; Chen, Yu-Zong; Li, Lu-Lu; Tan, Chun-Yan; Liu, Hong-Xia; Gao, Chun-Mei; Jiang, Yu-Yang
Chinese Chemical Letters, 2013 , vol. 24, # 8 p. 677 - 680
反应条件
1: BINAP / Pd(OAc)2 2: Ba(OH)2*8H2O / methanol / 2 h / 80 °C 3: POCl3 View Scheme
参考文献
Synlett, , # 13 p. 2391 - 2393
反应条件
1: 58 percent / K2CO3; Cu; pyridine / pentan-1-ol / 5 h / Heating 2: 77 percent / POCl3 / 6 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 60, # 27 p. 5737 - 5750
反应条件
1: BINAP / Pd(OAc)2 2: Ba(OH)2*8H2O / methanol / 2 h / 80 °C 3: POCl3 View Scheme
参考文献
Synlett, , # 13 p. 2391 - 2393
反应条件
1: Ba(OH)2*8H2O / methanol / 2 h / 80 °C 2: POCl3 View Scheme
参考文献
Synlett, , # 13 p. 2391 - 2393
反应条件
phosphorus pentachloride
参考文献
US1855302 , ;
DE565411 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 1176
参考文献
Guetzoyan, Lucie; Yu, Xiao-Min; Ramiandrasoa, Florence; Pethe, Stephanie; Rogier, Christophe; Pradines, Bruno; Cresteil, Thierry; Perree-Fauvet, Martine; Mahy, Jean-Pierre
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 23 p. 8032 - 8039
反应条件
phenol T=120°C; 2 h;
参考文献
Guo, Yunkui
Tetrahedron Letters, 1995 , vol. 36, # 37 p. 6651 - 6654
反应条件
1: Raney nickel; methanol. KOH-solution / Hydrogenation 2: hydrochloric acid; iron (III)-chloride; water View Scheme
参考文献
Fedorow
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 591,593;engl.Ausg.S.639,641
反应条件
in various solvent(s) T=120°C; 1.5 h;
参考文献
Leon; Garbay-Jaureguiberry; Lambert; Le Pecq; Rogues
Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 1021 - 1026
