2-溴-3-氧代丁酸乙酯合成路线 （共 43 条）
反应条件
in chloroform T=60°C; 0.5 h;
参考文献
Veber, M.; Duong, K.N.-V.; Gaudemer, A.; Johnson, M. D.
Journal of Organometallic Chemistry, 1981 , vol. 209, # 3 p. 393 - 400
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.2 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Zav'yalov; Dorofeeva; Rumyantseva; Kulikova; Ezhova; Kravchenko; Zavozin
Pharmaceutical Chemistry Journal, 2001 , vol. 35, # 2 p. 96 - 98
反应条件
in ethanol 2 h; RefluxInert atmosphere;
参考文献
Li, Guoliang; He, Yundong; Zhou, Wenbo; Wang, Peng; Zhang, Yong; Tong, Weiguang; Wu, Haigang; Liu, Mingyao; Ye, Xiyun; Chen, Yihua
Heterocycles, 2014 , vol. 89, # 2 p. 453 - 464
反应条件
T=85 - 90°C; 20 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Baires, S. V.; Ivanov, V. B.; Vil'danova, L. T.; Ivanov, B. E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1987 , vol. 36, # 4 p. 879
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1987 , # 4 p. 953
反应条件
in ethanol 6 h; Heating;
参考文献
Compton, Victoria J.; Meakins, G. Denis; Raybould, Amanda J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 15 p. 2029 - 2032
参考文献
Andreani; Bonazzi; Rambaldi; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 271 - 274
反应条件
1: acetic acid; hydrogen bromide / 100 °C 2: ethanol / 1 h / 20 °C View Scheme
参考文献
Makena, Anne; Van Berkel, Sander S.; Lejeune, Clarisse; Owens, Raymond J.; Verma, Anil; Salimraj, Ramya; Spencer, James; Brem, Juergen; Schofield, Christopher J.
ChemMedChem, 2013 , vol. 8, # 12 p. 1923 - 1929
参考文献
Tronow; Akiwis; Orlowa
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1929 , vol. 61, p. 349
Chem. Zentralbl., 1929 , vol. 100, # II p. 2550
参考文献
Gharde, A. D.; Ghiya, B. J.
Journal of the Indian Chemical Society, 1995 , vol. 72, # 3 p. 209 - 210
