(1R,2S,4S)-rel-双环[2.2.1]庚烷-2-醇,4-甲基苯磺酸酯合成路线 (共 12 条)
反应条件
hexafluoroisopropyl alcohol; water T=24.9°C; ΔG, ΔH, ΔS; Rate constantThermodynamic data;
参考文献
Schneider, Hans-Joerg; Becker, Norman; Schmidt, Guenther; Thomas, Fred
Journal of Organic Chemistry, 1986 , vol. 51, # 19 p. 3602 - 3607
反应条件
water T=31.2°C; Rate constant;
参考文献
McManus, Samuel P.; Smith, Maurice R.; Shankweiler, Jean M.; Hoffman, Robert V.
Journal of Organic Chemistry, 1988 , vol. 53, # 1 p. 141 - 148
反应条件
water in 1,4-dioxane Product distribution;
参考文献
Flury, Peter; Grob, Cyril A.
Helvetica Chimica Acta, 1983 , vol. 66, # 7 p. 1971 - 1980
参考文献
Grob, Cyril A.; Waldner, Adrian
Tetrahedron Letters, 1981 , vol. 22, # 34 p. 3235 - 3238
反应条件
water in ethanol T=70°C; other solvent, ΔH(excit.), ΔS(excit.), substituent effect; Thermodynamic dataKinetics;
参考文献
Grob, Cyril A.; Guenther, Bettina; Hanreich, Reinhard
Helvetica Chimica Acta, 1982 , vol. 65, # 7 p. 2110 - 2117
反应条件
water; triethylamine in 1,4-dioxane T=90°C; 3.3 h; Product distribution;
参考文献
Fischer, Walter; Grob, Cyril A.; Sprecher, Georg von; Waldner, Adrian
Helvetica Chimica Acta, 1980 , vol. 63, # 4 p. 928 - 937
反应条件
potassium tert-butylate in dimethyl sulfoxide T=80°C; 5 h; effect of triglyme as solvent and of 18-crown-6; Product distribution;
参考文献
Bartsch, Richard A.; Lee, Jong Gun
Journal of Organic Chemistry, 1990 , vol. 55, # 18 p. 5247 - 5252
反应条件
1: aqueous acetone View Scheme
参考文献
Winstein; Trifan
Journal of the American Chemical Society, 1952 , vol. 74, p. 1154,1159
Journal of the American Chemical Society, 1949 , vol. 71, p. 2953
反应条件
in tetrahydrofuran T=100°C; 4 h; Further byproducts given;
参考文献
Chemistry Letters, , p. 935 - 938
反应条件
in tetrahydrofuran T=100°C; 4 h; Further byproducts given;
参考文献
Takeuchi, Ken'ichi; Kato,Yukari; Moriyama, Takamasa; Okamoto, Kunio
Chemistry Letters, 1981 , p. 935 - 938