(S)-n-boc-3-氨基-4-羟基丁酸合成路线 （共 9 条）
反应条件
aq. CsCO3 in acetone T=20°C; 3 h;
参考文献
Synlett, , # 6 p. 797 - 800
反应条件
1: 95 percent / diisopropyl carbodiimide / ethyl acetate / 2 h 2: NaBH4 / tetrahydrofuran / 16 h / 20 °C 3: aq. CsCO3 / acetone / 3 h / 20 °C View Scheme
参考文献
Synlett, , # 6 p. 797 - 800
反应条件
1: NaBH4 / tetrahydrofuran / 16 h / 20 °C 2: aq. CsCO3 / acetone / 3 h / 20 °C View Scheme
参考文献
Synlett, , # 6 p. 797 - 800
反应条件
1: triethylamine / 1,4-dioxane; water / 0 - 20 °C 2: triethylamine / tetrahydrofuran / 0 °C 3: sodium tetrahydroborate / water / 1 h / 20 °C 4: palladium 10 on activated carbon; hydrogen / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 7 p. 2133 - 2140
反应条件
1: triethylamine / tetrahydrofuran / 0 °C 2: sodium tetrahydroborate / water / 1 h / 20 °C 3: palladium 10 on activated carbon; hydrogen / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 7 p. 2133 - 2140
反应条件
palladium 10 on activated carbon; hydrogen T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 7 p. 2133 - 2140
反应条件
1: sodium tetrahydroborate / water / 1 h / 20 °C 2: palladium 10 on activated carbon; hydrogen / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 7 p. 2133 - 2140
反应条件
1: With triethylamine in tetrahydrofuran 2: With sodium tetrahydroborate in water
参考文献
Tetrahedron Letters, , vol. 43, # 19 p. 3489 - 3492
反应条件
trifluoroacetic acid in toluene
参考文献
Tetrahedron Letters, , vol. 43, # 19 p. 3489 - 3492
