1beta-甲基-1-苯基环己烷合成路线 （共 49 条）
反应条件
aluminum tri-bromide; bromine
参考文献
Bodroux
Annales de Chimie (Cachan, France), 1929 , vol. <10> 11, p. 519,525
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1928 , vol. 186, p. 1005
反应条件
1: 62 percent / anhydrous aluminium chloride / CCl4 / 1.) 0-5 deg C; 2.) rt, 2h 2: 45 percent / m-chloroperbenzoic acid / CH2Cl2 / 1.) 0 deg C; 2.) in dark, rt, 10 days 3: 93 percent / 4M sodium hydroxide / 6 h / Heating View Scheme
参考文献
Sidorowa
Zhurnal Obshchei Khimii, 1951 , vol. 21, p. 869,870; engl. Ausg. S. 951, 952
参考文献
Kasanskii et al.
Azerbajdzansk. chim. Z.Chem.Abstr., 1959 , # 5 p. 3,7
Azerbajdzansk. chim. Z.Chem.Abstr., 1961 , p. 13341
参考文献
Kasanskii et al.
Azerbajdzansk. chim. Z.Chem.Abstr., 1959 , # 5 p. 3,7
Azerbajdzansk. chim. Z.Chem.Abstr., 1961 , p. 13341
反应条件
platinum on activated charcoal T=180°C; Hydrogenation;
参考文献
Zhurnal Obshchei Khimii, , vol. 26, p. 3302,3303; engl. Ausg. S. 3673, 3674
反应条件
sulfuric acid
T=0°C; 3 h;
参考文献
Tsuda, Toshiro; Senba, Noriaki; Uratani, Takahiro
Patent: US2013/253228 A1, 2013 ;
Location in patent: Paragraph 0436; 0437 ;
反应条件
aluminium trichloride
参考文献
Zukerwanik; Ssidorowa
Zhurnal Obshchei Khimii, 1938 , vol. 8, p. 1899,1901
Chem. Zentralbl., 1940 , vol. 111, # I p. 1189
反应条件
in n-heptane; dichloromethane
T=20°C; 0.333333 h;
参考文献
Mahoney, Stuart J.; Lou, Tiantong; Bondarenko, Ganna; Fillion, Eric
Organic Letters, 2012 , vol. 14, # 13 p. 3474 - 3477
反应条件
sulfuric acid
T=20°C; Friedel-Crafts alkylation; 3 h;
参考文献
Fortin, Jessica S.; Cote, Marie-France; Lacroix, Jacques; Desjardins, Michel; Petitclerc, Eric; C.-Gaudreault, Rene
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 15 p. 7277 - 7290
反应条件
1: phenyl-(9-BBN) With lithium tert-butylate in 2-methyl-propan-1-ol; benzene
T=20°C; 0.333333 h; Schlenk techniqueInert atmosphere;
2: 1-bromo-1-methylcyclohexane With [(diglyme)NiBr2]; 4,4'-di-tert-butyl-2,2'-dipyridyl in 2-methyl-propan-1-ol; benzene
T=20 - 40°C; Suzuki Coupling; 28.5 h; Schlenk techniqueInert atmosphere; ConcentrationReagent/catalystSolvent;
参考文献
Zultanski, Susan L.; Fu, Gregory C.
Journal of the American Chemical Society, 2013 , vol. 135, # 2 p. 624 - 627
