acetyl chloride in ethanol 10 h; Ambient temperature;

1: 80 percent / acetyl chloride / ethanol / 10 h / Ambient temperature 2: 89 percent / polyphosphoric acid View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '8973685', constants.ctx, '0')">zinc</a> <br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 92 percent / p-toluenesulfonic acid / CH₂Cl₂ / 1 h / 0 &deg;C<br />2: 1.) LDA / 1.) THF, -78 deg C, 0.5 h, 2.) 0.5 h<br /> <br /> &nbsp;