3-碘-1-(苯磺酰)吲哚合成路线 （共 24 条）
反应条件
sodium hydroxide; tetrabutylammomium bromide in tetrahydrofuran; water T=0 - 20°C; 3 h;
参考文献
Industrial Technology Research Institute; YUNG SHIN PHARM. IND. CO., LTD.
Patent: US2006/106041 A1, 2006 ;
Location in patent: Page/Page column 3 ;
反应条件
pyridine; iodine; bis-[(trifluoroacetoxy)iodo]benzene in dichloromethane 2 h; Ambient temperature;
参考文献
Benhida, Rachid; Blanchard, Pierre; Fourrey, Jean-Louis
Tetrahedron Letters, 1998 , vol. 39, # 38 p. 6849 - 6852
反应条件
2-lithio-2-methyl-propionitrile; copper(II) sulfate
参考文献
Moriarty, Robert M.; Ku, Y. Y.; Sultana, M.; Tuncay, Atilla
Tetrahedron Letters, 1987 , vol. 28, # 27 p. 3071 - 3074
反应条件
1: FeCl3; NaI / acetonitrile / 6 h 2: 0.95 g / NaOH; tetrabutylammonium hydrogensulfate / benzene / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 14 p. 3242 - 3247
反应条件
1.1: TBAF / tetrahydrofuran / 0.25 h 1.2: NIS / CH2Cl2 / 0.17 h 2.1: 1.73 g / aq.NaOH; Bu4NBr / toluene / 2 h / 20 °C View Scheme
参考文献
Organic letters, , vol. 4, # 5 p. 815 - 817
反应条件
n-butyllithium; iodine; lithium diisopropyl amide Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 34, # 11 p. 2095 - 2108
反应条件
bromocyane; lithium diisopropyl amide in tetrahydrofuran Substitution;
参考文献
Liu; Gribble
Tetrahedron Letters, 2000 , vol. 41, # 45 p. 8717 - 8721
反应条件
1: 96 percent / LDA; I2 2: 83 percent / P(o-tolyl)3; K2CO3 / Pd(OAc)2 / acetone; H2O / 5 h / 70 °C 3: 89 percent / Mg / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 45 p. 8717 - 8721
反应条件
1: tert-butyllithium / tetrahydrofuran; pentane / 0.08 h / -100 °C 2: tetrahydrofuran / 6 h / -100 - 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 5 p. 757 - 761
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Suzuki-Miyaura coupling; 15 h; Heating;
参考文献
Cui, Yi; Li, Fenghong; Lu, Zheng-Hong; Wang, Suning
Dalton Transactions, 2007 , # 25 p. 2634 - 2643
