1-甲氧基-4-(2-甲氧基乙基)苯合成路线 （共 15 条）
反应条件
hydrogen bromide T=100°C; im Rohr;
参考文献
Spaeth; Sobel
Monatshefte fuer Chemie, 1920 , vol. 41, p. 89
参考文献
Spaeth; Sobel
Monatshefte fuer Chemie, 1920 , vol. 41, p. 89
反应条件
sodium hydride in tetrahydrofuran
T=55°C; 1.5 h;
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Perlmutter, Patrick
Australian Journal of Chemistry, 1982 , vol. 35, # 7 p. 1469 - 1480
反应条件
N,N,N',N,-tetramethylethylenediamine; ((Me)N2N)Ni-Cl in tetrahydrofuran
T=20°C; Kumada-Corriu-Tamao coupling reaction; 2 h; Inert atmosphere;
参考文献
Vechorkin, Oleg; Proust, Valerie; Hu, Xile
Journal of the American Chemical Society, 2009 , vol. 131, # 28 p. 9756 - 9766
反应条件
Amberlyst 15
12 h; Reflux;
参考文献
Barontini; Proietti Silvestri; Nardi; Bovicelli; Pari; Gallucci; Spezia; Righi
Tetrahedron Letters, 2013 , vol. 54, # 37 p. 5004 - 5006
反应条件
Amberlyst 15
36 h; Reflux;
参考文献
Barontini; Proietti Silvestri; Nardi; Bovicelli; Pari; Gallucci; Spezia; Righi
Tetrahedron Letters, 2013 , vol. 54, # 37 p. 5004 - 5006
反应条件
1: 80 percent / LiAlH4 / diethyl ether; tetrahydrofuran
2: 72 percent / NaH / tetrahydrofuran / 1.5 h / 55 °C
View Scheme
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Perlmutter, Patrick
Australian Journal of Chemistry, 1982 , vol. 35, # 7 p. 1469 - 1480
反应条件
dodecacarbonyltriiron; 1,1,3,3-tetramethyldisiloxane in toluene
T=100°C; 2 h; Inert atmosphereSchlenk technique;
参考文献
Das, Shoubhik; Li, Yuehui; Junge, Kathrin; Beller, Matthias
Chemical Communications, 2012 , vol. 48, # 87 p. 10742 - 10744
反应条件
mono(bis(di-tert-butyl(4-(dimethylamino)phenyl)phosphonio)palladium(II))dichloride; caesium carbonate in water; toluene
T=100°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere;
参考文献
Fleury-Bregeot, Nicolas; Presset, Marc; Beaumard, Floriane; Colombel, Virginie; Oehlrich, Daniel; Rombouts, Frederik; Molander, Gary A.
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10399 - 10408
反应条件
in propionic acid
T=170°C; 6 h;
参考文献
Bird, C. W.; Brown, A. L.; Chan, C. C.
Tetrahedron, 1985 , vol. 41, # 20 p. 4685 - 4690
