3-(3-氯苯基)丙-2-炔-1-醇合成路线 (共 3 条)
反应条件
copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; triethylamine T=20°C; Sonogashira coupling; 12 h; Inert atmosphere;
参考文献
Parmar, Dixit; Matsubara, Hiroshi; Price, Kieran; Spain, Malcolm; Procter, David J.
Journal of the American Chemical Society, 2012 , vol. 134, # 30 p. 12751 - 12757
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; diisopropylamine 1.) RT, 30 min, 2.) 60 deg C, 24 h; Yield givenMultistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 11 p. 1999 - 2006
反应条件
(i) EtMgBr, (ii) /BRN= 1209228/; Multistep reaction;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 46, p. 954 - 959