1: 71 percent / CH2Cl2; cyclohexane / 96 h / 35 °C / Irradiation 2: 88 percent / p-TsOH / Ambient temperature 3: 1.) H2, 40 psi, 2.) pyridine / 1.) Raney nickel / 1.) methanol, acetic acid, 118 h, 2.) room temp 4: 1.) n-Bu4NF, 2.) pyridine / 1.) THF, 0 deg C to room temp, 2.) room temp View Scheme

1H-imidazole in N,N-dimethyl-formamide T=20°C; Hanessian's silylation; 14 h;

1H-imidazole; sodium methylate 1.) MeOH, 0 deg C; 2.) DMF, 25 deg C, 2 h, then 45 deg C, 10 h; Yield given. Multistep reaction;

1H-imidazole in N,N-dimethyl-formamide Ambient temperature; Yield given;

1: sodium methoxide / methanol 2: imidazole / dimethylformamide View Scheme

1: zinc; ammonium chloride; VO(salen) / methanol 2: sodium methoxide / methanol 3: imidazole / dimethylformamide View Scheme

1: HBr; acetic acid 2: zinc; ammonium chloride; VO(salen) / methanol 3: sodium methoxide / methanol 4: imidazole / dimethylformamide View Scheme