1,5-二甲基-3-(三氟甲基)-1H-吡唑合成路线 （共 9 条）
反应条件
1: methyl propen-2-yl ether; trifluoroacetic anhydride With pyridine in tert-butyl methyl ether T=0 - 5°C; 0.5 h; 2: methylhydrazine in tert-butyl methyl ether T=-20 - 20°C;
参考文献
Ebenbeck, Wolfgang; Rampf, Florian; Marhold, Albrecht
Patent: US2004/229929 A1, 2004 ;
Location in patent: Page 6 ;
反应条件
potassium tert-butylate in tetrahydrofuran T=20°C; 1.75 h;
参考文献
WO2007/71900 A1, ;
Page/Page column 89 ;
反应条件
in methanol; ethanol; acetic acid; toluene
反应条件
in various solvent(s) T=20°C; 0.75 h;
参考文献
Journal of Organic Chemistry, , vol. 73, # 9 p. 3523 - 3529
反应条件
in dichloromethane 2 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 40, # 6 p. 1087 - 1089
反应条件
in chloroform-d1 Mechanism;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 18, # 5 p. 788 - 795
Zhurnal Organicheskoi Khimii, , vol. 18, # 5 p. 909 - 916
反应条件
bromine; sodium acetate in chloroform T=0 - 20°C; 96 h;
参考文献
US2004/142820 A1, ;
Page 7 ;
反应条件
sodium bromide in acetic acid
参考文献
Nissan Chemical Industries, Ltd.
Patent: US5053517 A1, 1991 ;
