1,1,2,2-四溴乙烷合成路线 （共 111 条）
反应条件
tetramethylpiperidine; n-butyl lithium in tetrahydrofuran; hexane
Schlenk techniques used under N2 or Ar, THF soln. of (BrC5H4)2Fe (25.0 mmol) treated at -70°C with soln. of nBuLi (25.0 mmol), after 30 min TMP (25.0 mmol) added, stirred for 3 h at -30--40°C, C2H2Br4 (25.0 mmol) added at -70°C; allowed to warm to ambient temp. for >18 h, H2O added, aq. phase separated, extracted with Et2O, dried over MgSO4, evaporated, chromd. (neutral alumina, hexane), FcH removed by sublimation; NMR;
参考文献
Suenkel, Karlheinz; Bernhartzeder, Stefanie
Journal of Organometallic Chemistry, 2011 , vol. 696, # 8 p. 1536 - 1540
