反应条件
1: 3-chloro-4-fluoro-α,α,α-trifluorotoluene With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78 - -73°C; 1.41667 h; 2: carbon dioxide in tetrahydrofuran; hexane T=-78 - -75°C; 1 h; 3: With hydrogenchloride; water in tetrahydrofuran; hexane T=-4°C; 0.5 h; Product distribution / selectivity;
参考文献
Bachmann, Stephan; Hildbrand, Stefan; Jappy, James; Patel, Dinesh Maganbhai; Pfleger, Christophe; Tidswell, Robert John Ernest; Trussardi, Rene
Patent: US2009/306423 A1, 2009 ;
Location in patent: Page/Page column 8 ;