3-(2-羟基-2-丙基)苯酚合成路线 (共 16 条)
反应条件
in tetrahydrofuran T=0 - 20°C; 18 h; Inert atmosphere;
参考文献
VIDASYM, LLC; KAWAI, Megumi
Patent: WO2010/120698 A1, 2010 ;
Location in patent: Page/Page column 86-87 ;
反应条件
chloro-trimethyl-silane in tetrahydrofuran; diethyl ether T=0°C; 2 h; Yields of byproduct given;
参考文献
Rubottom, George M.; Kim, Chong-wan
Journal of Organic Chemistry, 1983 , vol. 48, # 9 p. 1550 - 1552
反应条件
sodium hydroxide; methylmagnesium bromide in tetrahydrofuran; water
反应条件
hydrogenchloride; sodium hydroxide; sodium periodate; Na2S2O4 in tetrahydrofuran; methanol; water; ethyl acetate; DDAO
参考文献
Hartsel, Joshua A.; Craft, Derek T.; Chen, Qiao-Hong; Ma, Ming; Carlier, Paul R.
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3127 - 3133
参考文献
Journal of the American Chemical Society, , vol. 99, p. 3401 - 3408
反应条件
acid Fuller's earth; acetone
参考文献
Justus Liebigs Annalen der Chemie, , vol. 413, p. 304
反应条件
chromium oxide-copper oxide barium oxide catalyst Hydrogenation;
参考文献
Gilman et al.
Journal of Organic Chemistry, 1954 , vol. 19, p. 1067,1073
反应条件
1: 2M NaOH / tetrahydrofuran; H2O / 1.5 h / 0 °C 2: Na2S2O4 / ethyl acetate; H2O 3: 2M HCl / methanol / 1.25 h / 100 °C 4: 82 percent / NaIO3 / H2O; ethyl acetate / 0.25 h View Scheme
参考文献
Corey, Paul F.; Trimmer, Robert W.; Biddlecom, William G.
Angewandte Chemie, 1991 , vol. 103, # 12 p. 1694 - 1696