1-(2-溴乙基)金刚烷合成路线 （共 12 条）
反应条件
N-bromosuccinmide; triphenylphosphine in benzene T=23°C; 12 h;
参考文献
Belser, Thomas; Stoehr, Meike; Pfaltz, Andreas
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8720 - 8731
反应条件
hydrogen bromide in sulfuric acid; water
参考文献
LUMMUS NOVOLEN TECHNOLOGY GMBH
Patent: US2010/267907 A1, 2010 ;
反应条件
hydrogen bromide in water
反应条件
aluminum tri-bromide in hexane
参考文献
Chemische Berichte, , vol. 95, p. 1039 - 1042
反应条件
1: sulfuric acid / 10 h / |Reflux 2: lithium aluminium tetrahydride / diethyl ether / 20 h / |Reflux 3: hydrogen bromide; sulfuric acid / 10 h / |Reflux View Scheme
参考文献
Synthetic Communications, , vol. 43, # 13 p. 1772 - 1777
反应条件
(i) Mg, THF, (ii) /BRN= 1209228/; Multistep reaction;
参考文献
Chakrabarti,J.K. et al.
Journal of Medicinal Chemistry, 1974 , vol. 17, p. 602 - 609
反应条件
1: H2, NaOH / Raney-Ni 2: Br2 View Scheme
参考文献
Stepanov,F.N. et al.
Journal of Organic Chemistry USSR (English Translation), 1969 , vol. 5, p. 2123 - 2125
Zhurnal Organicheskoi Khimii, 1969 , vol. 5, # 12 p. 2187 - 2189
反应条件
sodium hydroxide; hydrogen; nickel
参考文献
Stepanov,F.N. et al.
Journal of Organic Chemistry USSR (English Translation), 1969 , vol. 5, p. 2123 - 2125
Zhurnal Organicheskoi Khimii, 1969 , vol. 5, # 12 p. 2187 - 2189
反应条件
(i) Li, nBuBr, (ii) /BRN= 1900390/; Multistep reaction;
参考文献
Fieser; Nazer; Archer; Berberian; Slighter
Journal of medicinal chemistry, 1967 , vol. 10, # 4 p. 517 - 521
反应条件
(i) EtOH, (ii) KOH; Multistep reaction;
参考文献
Fieser; Nazer; Archer; Berberian; Slighter
Journal of medicinal chemistry, 1967 , vol. 10, # 4 p. 517 - 521
