5-羟基-4-甲氧基-2-甲基苯甲醛合成路线 （共 8 条）
反应条件
1: 73.7 percent / 30percent NaOH / ethanol / 3 h / Heating 2: 76.2 percent / perbenzoic acid / CH2Cl2 / 3 h / Heating 3: 76.44 percent / K2CO3 / acetone / 72 h / 75 °C / sealed tube View Scheme
参考文献
Kozlova, I. V.; Obol'nikova, E. A.; Chupina, L. N.; Bekker, A. R.; Samokhvalov, G. I.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 296 - 299
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 2 p. 351 - 354
反应条件
titanium tetrachloride in dichloromethane
T=20°C; 3 h;
参考文献
Kozlova, I. V.; Obol'nikova, E. A.; Chupina, L. N.; Bekker, A. R.; Samokhvalov, G. I.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 296 - 299
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 2 p. 351 - 354
参考文献
Scarpati, Maria Luisa; Bianco, Armandodoriano; Mascitelli, Livia; Passacantilli, Pietro
Synthetic Communications, 1990 , vol. 20, # 17 p. 2565 - 2572
反应条件
sulfuric acid
T=65 - 75°C; 17 h; demethylation;
参考文献
Waddell, Thomas G.; Rapoport, Henry
Phytochemistry (Elsevier), 1985 , vol. 24, # 3 p. 469 - 472
反应条件
1: TiCl4 / CH2Cl2 / Ambient temperature
2: conc. aq. HCl / CH2Cl2; diethyl ether / 0.5 h / 0 °C
3: 100 percent / alkaline hydrolysis
View Scheme
参考文献
Scarpati, Maria Luisa; Bianco, Armandodoriano; Mascitelli, Livia; Passacantilli, Pietro
Synthetic Communications, 1990 , vol. 20, # 17 p. 2565 - 2572
反应条件
1: NaOH
2: POCl3
3: conc.H2SO4 / 17 h / 65 - 75 °C / demethylation
View Scheme
参考文献
Waddell, Thomas G.; Rapoport, Henry
Phytochemistry (Elsevier), 1985 , vol. 24, # 3 p. 469 - 472
反应条件
1: POCl3
2: conc.H2SO4 / 17 h / 65 - 75 °C / demethylation
View Scheme
参考文献
Waddell, Thomas G.; Rapoport, Henry
Phytochemistry (Elsevier), 1985 , vol. 24, # 3 p. 469 - 472
反应条件
sodium hydroxide in ethanol
3 h; Heating;
参考文献
Kozlova, I. V.; Obol'nikova, E. A.; Chupina, L. N.; Bekker, A. R.; Samokhvalov, G. I.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 296 - 299
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 2 p. 351 - 354
