2-甲基-4H-1-苯并噻喃-4-酮合成路线 （共 20 条）
反应条件
sulfuric acid T=60°C; 24 h;
参考文献
Nakazumi; Ueyama; Sonoda; Kitao
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 8 p. 2323 - 2324
反应条件
phosphorous pentoxide; phosphoric acid
T=70°C; 3.25 h; Inert atmosphere;
参考文献
Zhang, Youlai; Tanimoto, Hiroki; Nishiyama, Yasuhiro; Morimoto, Tsumoru; Kakiuchi, Kiyomi
Synlett, 2012 , # 3 p. 367 - 370
反应条件
iodine in dimethyl sulfoxide
1.5 h; Heating;
参考文献
Patonay; Adam; Levai; Koever; Nemeth; Peters
Journal of Organic Chemistry, 2001 , vol. 66, # 7 p. 2275 - 2280
反应条件
hydrogenchloride in ethanol; water
Decarboxylation; 3 h; Heating;
参考文献
Jung, Jae-Chul; Kim, Ju-Cheun; Park, Oee-Sook
Synthetic Communications, 2000 , vol. 30, # 7 p. 1193 - 1203
参考文献
Holshouser, Mark H.; Loeffler, Larry J.; Hall, Iris H.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 853 - 858
参考文献
Nakazumi, Hiroyuki; Asada, Akira; Kitao, Teijiro
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 7 p. 2046 - 2049
反应条件
ethylenediamine in ethanol
2 h; Heating;
参考文献
Coombes, Richard C.; Fenton, David E.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 14, p. 139 - 142
反应条件
in tetrahydrofuran
Wittig cyclization; 16 h; Heating;
参考文献
Kumar, Pradeep; Bodas, Mandar S
Tetrahedron, 2001 , vol. 57, # 48 p. 9755 - 9758
反应条件
in toluene
10 h; Heating;
参考文献
Kumar, Pradeep; Rao, Ashok T.; Pandey, Bipin
Journal of the Chemical Society, Chemical Communications, 1992 , # 21 p. 1580 - 1581
反应条件
1: imidazole / CH2Cl2 / 0 - 20 °C
2: 80 percent / tetrahydrofuran / 16 h / Heating
View Scheme
参考文献
Kumar, Pradeep; Bodas, Mandar S
Tetrahedron, 2001 , vol. 57, # 48 p. 9755 - 9758
