2,6-双(溴甲基)吡啶合成路线 （共 27 条）
反应条件
1: With hydrogen bromide in water T=125°C; 2: With sodium hydrogencarbonate in water pH=8;
参考文献
Xue, Fengtian; Fang, Jianguo; Delker, Silvia L.; Li, Huiying; Martasek, Pavel; Roman, Linda J.; Poulos, Thomas L.; Silverman, Richard B.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2039 - 2048
反应条件
1: With N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane Heating; 2: With phosphorous acid diethyl ester; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=25°C; 5 h;
参考文献
Liu; Chen; Deng; Tu
Synthesis, 2001 , # 14 p. 2078 - 2080
反应条件
hydrogen bromide 15 h; Heating;
参考文献
European Journal of Inorganic Chemistry, , # 12 p. 3284 - 3291
反应条件
1: ethanolic HCl 2: lithium alanate; diethyl ether 3: sulfuric acid; aqueous hydrobromic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 75, p. 3830
反应条件
1: lithium alanate; diethyl ether 2: sulfuric acid; aqueous hydrobromic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 75, p. 3830
反应条件
tetrachloromethane; N-bromosuccinmide; dibenzoyl peroxide
参考文献
Journal of the American Chemical Society, , vol. 75, p. 3830
反应条件
diethyl ether anschliessend Behandeln mit Brom;
参考文献
Journal of the American Chemical Society, , vol. 75, p. 3830
反应条件
1: sodium tetrahydroborate / ethanol / 13 h / 0 - 20 °C / |Reflux 2: hydrogen bromide / 15 h / |Reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 54, # 43 p. 5771 - 5774
反应条件
1: thionyl chloride 2: sodium tetrahydroborate / ethanol / 13 h / 0 - 20 °C / |Reflux 3: hydrogen bromide / 15 h / |Reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 54, # 43 p. 5771 - 5774
