phosphate buffer in tetrahydrofuran; water 504 h; other pH; Product distributionMechanism;

borate buffer; anhydrous carbonate in tetrahydrofuran; water pH 10.0;

phosphate buffer in chloroform 4 h; pH 6;

1: 88 percent / tert-butyl hydroperoxide, VO(acac)2 / benzene / 3 h / Heating 2: 70 percent / dimethyl sulfoxide, trifluoroacetic anhydride / CH2Cl2 / 0.67 h / -65 °C 3: 44 percent / Br2 / CHCl3 / -65 °C 4: 2.) DBN / 1.) CCl4, 1 h, 2.) ether, room temperature, 10 h 5: 49 percent / aq. phosphate buffer / CHCl3 / 4 h / pH 6 View Scheme

1: 44 percent / Br2 / CHCl3 / -65 °C 2: 2.) DBN / 1.) CCl4, 1 h, 2.) ether, room temperature, 10 h 3: 49 percent / aq. phosphate buffer / CHCl3 / 4 h / pH 6 View Scheme

1: 70 percent / dimethyl sulfoxide, trifluoroacetic anhydride / CH2Cl2 / 0.67 h / -65 °C 2: 44 percent / Br2 / CHCl3 / -65 °C 3: 2.) DBN / 1.) CCl4, 1 h, 2.) ether, room temperature, 10 h 4: 49 percent / aq. phosphate buffer / CHCl3 / 4 h / pH 6 View Scheme

1: 2.) DBN / 1.) CCl4, 1 h, 2.) ether, room temperature, 10 h 2: 49 percent / aq. phosphate buffer / CHCl3 / 4 h / pH 6 View Scheme