2-乙烯基环丙烷-1,1-二羧酸二乙酯合成路线 （共 30 条）
参考文献
Hosomi; Mikami; Sakurai
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 9 p. 2784 - 2794
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Heating;
参考文献
Ashton; Canning Meurer; Cantone; Field; Hannah; Karkas; Liou; Patel; Perry; Wagner; Walton; Tolman
Journal of Medicinal Chemistry, 1988 , vol. 31, # 12 p. 2304 - 2315
反应条件
in tetrahydrofuran; acetic acid-(1-ethyl-cyclohexyl ester); water
参考文献
MERCK and CO. INC.
Patent: EP159264 B1, 1991 ;
反应条件
1: 94 percent / 480 °C 2: KOH / H2O; ethanol / 6 h / Heating 3: 180 °C 4: 79 percent / LiAlH4 / diethyl ether View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 56, # 9 p. 2784 - 2794
反应条件
potassium hydroxide in dichloromethane
参考文献
Emery Industries, Inc.
Patent: US4252739 A1, 1981 ;
反应条件
sodium ethanolate in ethanol
参考文献
Hosomi; Mikami; Sakurai
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 9 p. 2784 - 2794
反应条件
potassium hydroxide; Aliquatreg; 336
参考文献
Emery Industries, Inc.
Patent: US4252739 A1, 1981 ;
反应条件
sodium hydride in tetrahydrofuran
T=70°C;
参考文献
Sarker, Prodip; Rehman, Saif U. R.; Rimmer, Stephen
Journal of Polymer Science, Part A: Polymer Chemistry, 2013 , vol. 51, # 8 p. 1822 - 1830
反应条件
potassium hydroxide in dichloromethane
参考文献
Emery Industries, Inc.
Patent: US4252739 A1, 1981 ;
反应条件
1: diethyl malonate With sodium ethanolate in ethanol; toluene
T=20°C; 0.5 h;
2: (Z)-1,4-Ditosyloxy-2-butene in ethanol; toluene
T=20°C; 3.5 h;
3: With sodium hydroxide in ethanol; water; toluene
1 h;
参考文献
API Corporation
Patent: EP2537825 A1, 2012 ;
Location in patent: Page/Page column 35 ;
