1-叔丁基-7-噁双环[4.1.0]庚烷合成路线 （共 14 条）
反应条件
1,3-dimethyl-imidazolidin-2-one; toluene-4-sulfonic acid in dichloromethane T=20°C; 2 h; regioselective reaction;
参考文献
Chapman, Helen A.; Herbal, Karim; Motherwell, William B.
Synlett, 2010 , # 4 art. no. D37609ST, p. 595 - 598
反应条件
methanol; toluene-4-sulfonic acid in dichloromethane 0.25 h; Ambient temperature; Further byproducts given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1607 - 1616
反应条件
boron trifluoride diethyl etherate in dichloromethane T=0°C; 0.0166667 h; var. reagents, solvents, temperatures and reaction times; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1607 - 1616
反应条件
potassium hydroxide; trichloroacetic acid 1.) cyclohexane, r.t.; 2.) THF, r.t., 5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Corona, Tiberio; Crotti, Paolo; Ferretti, Maria; Macchia, Franco
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1607 - 1616
反应条件
1: tert.-butylhydroperoxide With palladium diacetate; potassium carbonate in dichloromethane
T=0°C; 1 h;
2: 1-tert-Butylcyclohexene in dichloromethane
T=0°C; 72 h; Further stages.;
参考文献
Yu, Jin-Quan; Corey
Organic Letters, 2002 , vol. 4, # 16 p. 2727 - 2730
反应条件
disodium hydrogenphosphate; 2,2,2-trifluoroethanol; dihydrogen peroxide
5 h; Heating;
参考文献
Van Vliet; Arends; Sheldon
Synlett, 2001 , # 2 p. 248 - 250
反应条件
trichloroacetic acid in dichloromethane
T=25°C; 0.333333 h;
参考文献
Corona, Tiberio; Crotti, Paolo; Macchia, Franco; Ferretti, Maria
Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 377 - 379
反应条件
potassium hydroxide in dimethyl sulfoxide
T=100°C; 168 h; Further byproducts given. Yields of byproduct given;
参考文献
Corona, Tiberio; Crotti, Paolo; Ferretti, Maria; Macchia, Franco
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1607 - 1616
反应条件
trichloroacetic acid in dichloromethane
0.25 h; Ambient temperature; Further byproducts given;
参考文献
Corona, Tiberio; Crotti, Paolo; Ferretti, Maria; Macchia, Franco
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1607 - 1616
反应条件
1: 42 percent / trichloroacetic acid / CH2Cl2 / 0.33 h / 25 °C
2: 0.075 g / LiAlH4 / diethyl ether / 1 h / Ambient temperature
View Scheme
参考文献
Corona, Tiberio; Crotti, Paolo; Macchia, Franco; Ferretti, Maria
Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 377 - 379
