6-溴-2,3-二氢-1H-茚-1-醇合成路线 （共 20 条）
反应条件
1: 77 percent / H2SO4 (20percent), ethylene glycol / 20 h / 75 °C View Scheme
参考文献
Miller, R. Bryan; Frincke, James M.
Journal of Organic Chemistry, 1980 , vol. 45, # 26 p. 5312 - 5315
反应条件
toluene-4-sulfonic acid in benzene Heating;
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
1: 87 percent / p-TsOH / benzene / 2 h / Heating 2: 4 percent / Pseudomonas putida UV4 / 7 h View Scheme
参考文献
Boyd, Derek R.; Sharma, Narain D.; Bowers, Nigel I.; Boyle, Rosemary; Harrison, John S.; Lee, Kyoung; Bugg, Timothy D.H.; Gibson, David T.
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 8 p. 1298 - 1307
反应条件
sodium borohydride in methanol
参考文献
Iwanowicz, Edwin J.; Watterson, Scott H.; Dhar, T.G. Murali; Pitts, William J.; Gu, Henry H.
Patent: US2002/40022 A1, 2002 ;
反应条件
1: H2 / Pd/C / methanol
2: (COCl)2 / CH2Cl2
3: aluminum trichloride / CH2Cl2
4: sodium borohydride / methanol
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Hao, Jinsong; Neustadt, Bernard; Arik, Leyla; Foster, Carolyn J.; Lachowicz, Jean; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1333 - 1336
反应条件
1: piperidine / pyridine
2: H2 / Pd/C / methanol
3: (COCl)2 / CH2Cl2
4: aluminum trichloride / CH2Cl2
5: sodium borohydride / methanol
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Hao, Jinsong; Neustadt, Bernard; Arik, Leyla; Foster, Carolyn J.; Lachowicz, Jean; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1333 - 1336
反应条件
1: (COCl)2 / CH2Cl2
2: aluminum trichloride / CH2Cl2
3: sodium borohydride / methanol
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Hao, Jinsong; Neustadt, Bernard; Arik, Leyla; Foster, Carolyn J.; Lachowicz, Jean; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1333 - 1336
反应条件
1: aluminum trichloride / CH2Cl2
2: sodium borohydride / methanol
View Scheme
参考文献
Matasi, Julius J.; Caldwell, John P.; Hao, Jinsong; Neustadt, Bernard; Arik, Leyla; Foster, Carolyn J.; Lachowicz, Jean; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1333 - 1336
反应条件
1: 95 percent / KOH / acetic acid; H2O; tetrahydrofuran
2: 85 percent / 165 °C
3: thionyl chloride
4: 91 percent / AlCl3 / CS2
5: 89 percent / NaBH4 / ethanol / 25 °C
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
1: 85 percent / 165 °C
2: thionyl chloride
3: 91 percent / AlCl3 / CS2
4: 89 percent / NaBH4 / ethanol / 25 °C
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
