8-氟-1,2,3,4-四氢喹啉合成路线 (共 3 条)
反应条件
1: With triethylsilane; trifluoroacetic acid
T=20°C;
2: With sodium hydroxide in water
参考文献
Taisho Pharmaceutical Co. Ltd.
Patent: EP2172453 A1, 2010 ;
Location in patent: Page/Page column 10-11 ;
EP 2172453 A1
反应条件
hydrogen; platinum(IV) oxide in methanol
参考文献
Rae, Ian D.; Staffa, Alfred; Diz, Agustin C.; Giribet, Claudia G.; Azua, Martin C. Ruiz de; Contreras, Ruben H.
Australian Journal of Chemistry, 1987 , vol. 40, # 12 p. 1923 - 1940
反应条件
hydrogen; platinum(IV) oxide in trifluoroacetic acid
参考文献
Hoenel, Michael; Vierhapper, Friedrich W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1933 - 1939