2-溴-1-(溴甲基)-4-甲基苯合成路线 （共 5 条）
反应条件
tetrabutyl ammonium fluoride in acetonitrile T=0 - 20°C;
参考文献
Chaumontet, Manon; Piccardi, Riccardo; Audic, Nicolas; Hitce, Julien; Peglion, Jean-Louis; Clot, Eric; Baudoin, Olivier
Journal of the American Chemical Society, 2008 , vol. 130, # 45 p. 15157 - 15166
反应条件
carbon tetrabromide; triphenylphosphine in tetrahydrofuran; dichloromethane
T=0°C; 1 h;
参考文献
Chaumontet, Manon; Piccardi, Riccardo; Audic, Nicolas; Hitce, Julien; Peglion, Jean-Louis; Clot, Eric; Baudoin, Olivier
Journal of the American Chemical Society, 2008 , vol. 130, # 45 p. 15157 - 15166
反应条件
bromine in tetrachloromethane
T=-10°C; 0.5 h; reaction regioselectivity; a series of reagents; Product distributionMechanism;
参考文献
Bee, Lim Keow; Garratt, Peter J.; Mansuri, Muzamil M.
Journal of the American Chemical Society, 1980 , vol. 102, # 23 p. 7076 - 7079
反应条件
1: sodium tetrahydroborate / methanol / 0.33 h / 0 °C
2: phosphorus tribromide / diethyl ether / 3 h / 0 °C
View Scheme
参考文献
Dai, Yao; Feng, Xiujuan; Liu, Hesong; Jiang, Hua; Bao, Ming
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 10068 - 10077
反应条件
1: dimethylsulfide borane complex / tetrahydrofuran / 20 °C / Inert atmosphere
2: phosphorus tribromide / dichloromethane / 50 °C / Inert atmosphere
View Scheme
参考文献
Martin, Nicolas; Pierre, Cathleen; Davi, Michail; Jazzar, Rodolphe; Baudoin, Olivier
Chemistry - A European Journal, 2012 , vol. 18, # 15 p. 4480 - 4484
