1: cycloheptanone With lithium hexamethyldisilazane in tetrahydrofuran; pentane T=-78°C; 0.5 h; 2: bromoacetic acid methyl ester in tetrahydrofuran; pentane T=-78°C; 2 h;

1: 76 percent / copper(II)-pentandionate / benzene / 90 °C 2: 78 percent / (C2H5)3NHF / tetrahydrofuran / 1 h / 25 °C View Scheme

potassium carbonate in ethanol