2-(三甲基甲硅烷甲基)丙烯酸乙酯合成路线 （共 14 条）
反应条件
diazabicyclolt;5.4.0gt;undec-6-ene in diethyl ether 12 h; Ambient temperature;
参考文献
Trost,B.M.; Chan,D.M.
Journal of the American Chemical Society, 1983 , vol. 105, p. 2326
反应条件
boron trifluoride diethyl etherate in dichloromethane 1.) 30 min., O deg C, 2.) 2.5 h, room temperature;
参考文献
Haider, Akhtar
Synthesis, 1985 , # 3 p. 271 - 272
反应条件
potassium carbonate in water T=80°C; 0.75 h;
参考文献
Kirschleger, Bernard; Queignec, Rene
Synthesis, 1986 , # 11 p. 926 - 928
反应条件
potassium hydroxide in ethanol; water 2.5 h; Heating;
参考文献
Tetrahedron Letters, , vol. 21, p. 951 - 954
反应条件
1: 1.) n-BuLi, isopropylamine / 1) THF, 90 min, -78 deg C; 2) room temperature, 14 h 2: 92 percent / Et3N / diethyl ether / 1 h / 0 °C 3: 80 percent / diazabicyclo<5.4.0>undec-6-ene / diethyl ether / 12 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 105, p. 2326
反应条件
1: 92 percent / Et3N / diethyl ether / 1 h / 0 °C 2: 80 percent / diazabicyclo<5.4.0>undec-6-ene / diethyl ether / 12 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 105, p. 2326
反应条件
1: 1.) lithium / 1) ice-bath, THF, 45 min; 2) THF, 7 - 8 deg C (5 h), room temperature (40 h) 2: 1.) n-BuLi, isopropylamine / 1) THF, 90 min, -78 deg C; 2) room temperature, 14 h 3: 92 percent / Et3N / diethyl ether / 1 h / 0 °C 4: 80 percent / diazabicyclo<5.4.0>undec-6-ene / diethyl ether / 12 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 105, p. 2326
反应条件
in tetrahydrofuran 0.5 h; Heating;
参考文献
Alami, N. El.; Belaud, C.; Villieras, J.
Journal of Organometallic Chemistry, 1988 , vol. 353, p. 157 - 168
反应条件
1: 84 percent / 1.) NaH / benzene / 1.) 1.5 h, 2.) reflux, 5 h 2: 15 percent / KOH / ethanol; H2O / 2.5 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 21, p. 951 - 954
反应条件
1: 81 percent / 1.) EtONa / ethanol / 1.) 30 min. gentle heating; 2.) 24 h, reflux 2: 84 percent / 1.) NaH / benzene / 1.) 1.5 h, 2.) reflux, 5 h 3: 15 percent / KOH / ethanol; H2O / 2.5 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 21, p. 951 - 954
