3-[[叔丁氧羰基]氨基]-L-丙氨酸合成路线 （共 5 条）
反应条件
1: 61 percent / 4 N aq. NaOH / 2 h / 25 °C / pH 10-10.5 2: 79.5 percent / diethyl ether View Scheme
参考文献
Rich; Jasensky; Mueller; Anderson
Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 567 - 572
反应条件
1: 61 percent / 4 N aq. NaOH / 2 h / 25 °C / pH 10-10.5 2: 79.5 percent / diethyl ether 3: 100 percent / H2 / 10percent Pd/C / methanol / 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 5 p. 567 - 572
反应条件
sodium carbonate in tetrahydrofuran
参考文献
Ichikawa, Yoshiyasu; Ohara, Fumiyo; Kotsuki, Hiyoshizo; Nakano, Keiji
Organic Letters, 2006 , vol. 8, # 22 p. 5009 - 5012
反应条件
sodium carbonate in 1,4-dioxane; water Substitution;
参考文献
Zhang, Zhenyu; Aerschot, Arthur Van; Hendrix, Chris; Busson, Roger; David, Frank; Sandra, Pat; Herdewijn, Piet
Tetrahedron, 2000 , vol. 56, # 16 p. 2513 - 2522
反应条件
sodium hydroxide T=25°C; 2 h; pH 10-10.5;
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 5 p. 567 - 572
