1: Et3N / diethyl ether / 20 h / 25 °C 2: CH2Cl2 / 7 h / 25 °C 3: dry hydrogen chloride / CH2Cl2 / 10 h 4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C View Scheme

1: 79 percent / hydrochloric acid / acetone; H2O / 1 h / Heating 2: CH2Cl2 / 7 h / 25 °C 3: dry hydrogen chloride / CH2Cl2 / 10 h 4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C View Scheme

1: dry hydrogen chloride / CH2Cl2 / 10 h 2: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C View Scheme

1: CH2Cl2 / 7 h / 25 °C 2: dry hydrogen chloride / CH2Cl2 / 10 h 3: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C View Scheme

1: H2 / Pd/C / methanol 2: MnO2, 35percent H2SO4 View Scheme

1: 89 percent / H2 / Pd-C / methanol 2: 93 percent / tBuN(O)COPh / CH2Cl2; methanol View Scheme

1: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C 2: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature 3: 73 percent / NaOMe / methanol / 2 h / -15 °C 4: 87 percent / xylene / 4 h / Heating 5: 85 percent / HCl / methanol / 6 h / Heating 6: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether 7: 1.) BBr3; 2.) MeOH, H2SO4 (96percent) / 1.) CH2Cl2, room temp., 140 h; 2.) reflux, 48 h 8: 93 percent / benzoyl t-butyl nitroxide / methanol; CHCl3 / 16 h / Ambient temperature View Scheme

1: 97 percent / potassium carbonate / acetone / 8 h / Heating 2: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C 3: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature 4: 73 percent / NaOMe / methanol / 2 h / -15 °C 5: 87 percent / xylene / 4 h / Heating 6: 85 percent / HCl / methanol / 6 h / Heating 7: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether 8: 1.) BBr3; 2.) MeOH, H2SO4 (96percent) / 1.) CH2Cl2, room temp., 140 h; 2.) reflux, 48 h 9: 93 percent / benzoyl t-butyl nitroxide / methanol; CHCl3 / 16 h / Ambient temperature View Scheme

1: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether 2: 1.) BBr3; 2.) MeOH, H2SO4 (96percent) / 1.) CH2Cl2, room temp., 140 h; 2.) reflux, 48 h 3: 93 percent / benzoyl t-butyl nitroxide / methanol; CHCl3 / 16 h / Ambient temperature View Scheme

1: 88 percent / cc. H2SO4 / 20 h / Heating 2: 94 percent / ethanol / 3.5 h / 45 °C 3: 97 percent / potassium carbonate / acetone / 8 h / Heating 4: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C 5: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature 6: 73 percent / NaOMe / methanol / 2 h / -15 °C 7: 87 percent / xylene / 4 h / Heating 8: 85 percent / HCl / methanol / 6 h / Heating 9: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether 10: 1.) BBr3; 2.) MeOH, H2SO4 (96percent) / 1.) CH2Cl2, room temp., 140 h; 2.) reflux, 48 h 11: 93 percent / benzoyl t-butyl nitroxide / methanol; CHCl3 / 16 h / Ambient temperature View Scheme