2-氯-2,2-二甲基-2H-1,3-苯并恶嗪合成路线 （共 32 条）
反应条件
in 1,2-dichloro-ethane Heating; MechanismProduct distribution;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 10 p. 3020 - 3028
反应条件
in acetonitrile 1 h; Heating;
参考文献
Tachikawa, Ryuji; Wachi, Kazuyuki; Terada, Atsusuke
Heterocycles, 1981 , vol. 16, # 7 p. 1165 - 1168
反应条件
1: 89 percent / CH2Cl2 / 6 h / Heating 2: 96 percent / p-TSA / benzene / Heating View Scheme
参考文献
Tachikawa, Ryuji; Wachi, Kazuyuki; Terada, Atsusuke
Heterocycles, 1981 , vol. 16, # 7 p. 1165 - 1168
反应条件
in 1,2-dichloro-ethane 2 h; Heating; MechanismProduct distribution;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 10 p. 3020 - 3028
反应条件
in 1,2-dichloro-ethane Heating; MechanismProduct distribution;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 10 p. 3020 - 3028
反应条件
in 1,2-dichloro-ethane 12 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 2 p. 465 - 472
反应条件
toluene-4-sulfonic acid in acetone Heating / reflux;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2008/141119 A2, 2008 ;
Location in patent: Page/Page column 87-88 ;
WO 2008/141119 A2
反应条件
dimethyl sulfoxide 48 h; Ambient temperature;
参考文献
Tachikawa, Ryuji; Wachi, Kazuyuki; Terada, Atsusuke
Heterocycles, 1981 , vol. 15, # 1 p. 427 - 430
反应条件
48 h; Ambient temperature;
参考文献
Tachikawa, Ryuji; Wachi, Kazuyuki; Terada, Atsusuke
Heterocycles, 1981 , vol. 15, # 1 p. 427 - 430
反应条件
in 1,2-dichloro-ethane Heating; MechanismProduct distribution;
参考文献
Wachi, Kazuyuki; Terada, Atsusuke
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 10 p. 3020 - 3028
