N-(2-甲氧基乙基)-5-硝基吡啶-2-胺合成路线 （共 4 条）
参考文献
Gruenenthal GmbH; FRANK, Robert; Christoph, Thomas; Lesch, Bernhard; Lee, Jeewoo
Patent: US2013/29961 A1, 2013 ;
Location in patent: Paragraph 0726 ;
反应条件
triethylamine in dichloromethane
T=23°C; 3 h;
参考文献
Yun, Weiya; Ahmad, Mushtaq; Chen, Yingsi; Gillespie, Paul; Conde-Knape, Karin; Kazmer, Sonja; Li, Shiming; Qian, Yimin; Taub, Rebecca; Wertheimer, Stanley J.; Whittard, Toni; Bolin, David
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7205 - 7209
反应条件
1: trichlorophosphate; phosphorus pentachloride / 16 h / 60 °C
2: 1 h / 23 °C
View Scheme
参考文献
GRÜNENTHAL GMBH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; LESCH, Bernhard
Patent: WO2013/13815 A1, 2013 ;
WO 2013/013815 A1
反应条件
palladium 10 on activated carbon; hydrogen in ethyl acetate
T=20°C; 16 h;
参考文献
Gruenenthal GmbH; FRANK, Robert; Christoph, Thomas; Lesch, Bernhard; Lee, Jeewoo
Patent: US2013/29961 A1, 2013 ;
Location in patent: Paragraph 0727 ;
