4-甲氧基-N-乙基苯甲酰胺合成路线 （共 11 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 0.5 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 12 p. 3225 - 3235
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.333333 h; Sealed tubeMicrowave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
pyridine; tris-(dibenzylideneacetone)dipalladium(0); cis-1,3-bis[(di-tert-butylphosphino)methyl]cyclohexane in dichloromethane
T=45°C; P=750.075 Torr; 14 h; Inert atmosphere; chemoselective reaction;
参考文献
De La Fuente, Veronica; Godard, Cyril; Claver, Carmen; Castillon, Sergio
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 1971 - 1979
反应条件
potassium carbonate in tetrahydrofuran
Cooling with ice;
参考文献
Du, Ya; Hyster, Todd K.; Rovis, Tomislav
Chemical Communications, 2011 , vol. 47, # 44 p. 12074 - 12076
反应条件
1: thionyl chloride / 2 h / Reflux
2: potassium carbonate / tetrahydrofuran / Cooling with ice
View Scheme
参考文献
Du, Ya; Hyster, Todd K.; Rovis, Tomislav
Chemical Communications, 2011 , vol. 47, # 44 p. 12074 - 12076
反应条件
in water
T=25°C; ionic strengh 1.0 (KCl), 0.2M potassium phosphate buffer, various pH; Rate constantMechanism;
参考文献
Song, Byeong Doo; Jencks, William P.
Journal of the American Chemical Society, 1989 , vol. 111, # 22 p. 8479 - 8484
反应条件
in water; dimethyl sulfoxide
T=25°C; Kinetics;
参考文献
Um, Ik-Hwan; Kim, Kyung-Hee; Park, Hye-Ran; Fujio, Mizue; Tsuno, Yuho
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3937 - 3942
参考文献
Mndshojan et al.
Izvestiya Akademii Nauk Armyanskoi SSR, Khimicheskie Nauki, 1958 , vol. 11, p. 281,282, 283
Chem.Abstr., 1960 , p. 6679
反应条件
1: ethanol With sulfuryl dichloride; PPA
T=0°C; 0.0833333 h;
2: 2-methoxy 5-cyanobenzene T=0 - 150°C; 1 h; Product distribution / selectivity;
参考文献
DSM FINE CHEMICALS AUSTRIA NFG GMBH and CO KG
Patent: WO2004/31128 A1, 2004 ;
Location in patent: Page/Page column 9 ;
反应条件
1: carbonic acid diethyl ester With PPA
T=0°C; 0.0833333 h;
2: 2-methoxy 5-cyanobenzene T=0 - 150°C; 13 h; Product distribution / selectivity;
参考文献
DSM FINE CHEMICALS AUSTRIA NFG GMBH and CO KG
Patent: WO2004/31128 A1, 2004 ;
Location in patent: Page/Page column 10 ;
