N-(二甲基氨基-苯氧基-磷酰)-N-甲基-甲胺合成路线 （共 11 条）
反应条件
1: 1.) sec-BuLi / 1.) THF, -105 deg C, 1 h, 2.) THF, -105 deg C 2: 92 percent / sodium / liquid ammonia View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 37, # 9 p. 2564 - 2566
反应条件
sec.-butyllithium 1) cyclohexane, THF, -105 deg C, 1 h, 2) THF, -105 deg C, 1 h; Product distribution;
参考文献
Watanabe; Date; Kawanishi; Hori; Furukawa
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 10 p. 2637 - 2643
反应条件
boron trifluoride-methanol 1) 0 deg C, 1h, 2) RT, overnight;
参考文献
Ryu, Seungmin; Jackson, John A.; Thompson, Charles M.
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 4999 - 5002
反应条件
1: 1.) sec-BuLi / 1.) THF, -105 deg C, 1 h, 2.) THF, -105 deg C 2: formic acid / 1 h / Heating View Scheme
参考文献
Watanabe, Mitsuaki; Date, Mutsuhiro; Kawanishi, Kenji; Tsukazaki, Masao; Furukawa, Sunao
Chemical & Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2564 - 2566
反应条件
sodium hydride
1.) THF, 30 min, room temperature, 2.) THF, 12 h, room temperature;
参考文献
Watanabe; Date; Kawanishi; Hori; Furukawa
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 10 p. 2637 - 2643
反应条件
in acetonitrile
1.) 0 deg C, 1 h, 2.) RT, 1 h;
参考文献
Nasman; Kopola
Synthetic Communications, 1992 , vol. 22, # 17 p. 2491 - 2498
反应条件
methylenecarboxanilide
参考文献
Pedersen,E.B.; Lawesson,S.-O.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1974 , vol. 28, p. 1045 - 1054
参考文献
Perregaard,J. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1974 , vol. 93, p. 252 - 257
反应条件
sec.-butyllithium
1.) cyclohexane, THF, -105 deg C, 1 h, 2.) cyclohexane, THF, -105 deg C, 1 h;
参考文献
Watanabe; Date; Kawanishi; Hori; Furukawa
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 10 p. 2637 - 2643
反应条件
sec.-butyllithium
1) cyclohexane, THF, -105 deg C, 1 h, 2) THF, -105 deg C, 1 h; Product distribution;
参考文献
Watanabe; Date; Kawanishi; Hori; Furukawa
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 10 p. 2637 - 2643
