5-乙基-1,3-二甲基巴比妥酸合成路线 （共 12 条）
反应条件
hydrogenchloride; zinc in water
T=20°C; 0.5 h;
参考文献
Jursic, Branko S.; Stevens, Edwin D.
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2203 - 2210
反应条件
potassium hydroxide; [IrCP*Cl2]2
T=100°C; 14 h;
参考文献
Loefberg, Christian; Grigg, Ronald; Keep, Ann; Derrick, Andrew; Sridharan, Visuvanathar; Kilner, Colin
Chemical Communications, 2006 , # 48 p. 5000 - 5002
反应条件
triethylamine in chloroform
T=20°C; 24 h;
参考文献
Krasnov, K. A.; Slesarev, V. I.; Artem'eva, Z. L.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 7.2 p. 1402 - 1405
Zhurnal Obshchei Khimii, 1989 , vol. 25, # 7 p. 1553 - 1557
参考文献
Krasnov; Slesarev
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 4 p. 543 - 548
参考文献
Cope et al.
Journal of the American Chemical Society, 1941 , vol. 63, p. 356
反应条件
acetic anhydride; acetic acid
参考文献
Cope et al.
Journal of the American Chemical Society, 1941 , vol. 63, p. 356
反应条件
in 1,2-dichloro-benzene
Alkylation; 1 h;
参考文献
Krasnov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 2 p. 280 - 284
反应条件
1: pyridine / dichloromethane
2: sodium cyanoborohydride; acetic acid
View Scheme
参考文献
JOHNS HOPKINS UNIVERSITY; GUTHRIE, Daryl A.
Patent: WO2013/59194 A1, 2013 ;
反应条件
T=180°C; Alkylation; Condensation; 1 h;
参考文献
Krasnov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 2 p. 280 - 284
反应条件
triethylamine in chloroform
T=20°C; 4 h; further alkyl iodides; Product distributionRate constant;
参考文献
Krasnov, K. A.; Slesarev, V. I.; Artem'eva, Z. L.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 7.2 p. 1402 - 1405
Zhurnal Obshchei Khimii, 1989 , vol. 25, # 7 p. 1553 - 1557
