3-((输丁基二甲基甲硅烷基)氧)-丙醇合成路线 （共 25 条）
反应条件
sodium hydride in tetrahydrofuran
参考文献
UNIVERSITY OF PITTSBURGH
Patent: WO2005/117588 A2, 2005 ;
Location in patent: Page/Page column 31 ;
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; 24 h;
参考文献
Ikawa, Takashi; Hattori, Kazuyuki; Sajiki, Hironao; Hirota, Kosaku
Tetrahedron, 2004 , vol. 60, # 32 p. 6901 - 6911
反应条件
Ti-HMS; hydrogen; 5 percent palladium-carbon in methanol P=760 Torr; 4 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 39, # 51 p. 9461 - 9464
反应条件
1H-imidazole in N,N-dimethyl-formamide T=0 - 23°C; 12 h; Inert atmosphere;
参考文献
Jakobsche, Charles E.; Peris, Gorka; Miller, Scott J.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 35 p. 6707 - 6711
反应条件
sodium perchlorate monohydrate; water; sodium hydrogencarbonate in acetonitrile T=20°C; Electrolysis; chemoselective reaction;
参考文献
Vaxelaire, Carine; Souquet, Florence; Lannou, Marie-Isabelle; Ardisson, Janick; Royer, Jacques
European Journal of Organic Chemistry, 2009 , # 19 p. 3138 - 3140
反应条件
1: tert-Butyl-(3-iodo-propoxy)-dimethyl-silane With tert.-butyl lithium; oxygen in diethyl ether; pentane T=-78 - 23°C; Inert atmosphere; 2: C12H22FNO4 in diethyl ether; pentane T=-78°C; 1 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 47, # 35 p. 6707 - 6711
反应条件
in N,N-dimethyl-formamide
反应条件
1: 90 percent / DMAP; Et3N / CH2Cl2 / 24 h / 20 °C 2: 95 percent / H2 / Pd/C / methanol / 36 h / 20 °C / atmospheric pressure View Scheme
参考文献
Tetrahedron, , vol. 60, # 32 p. 6901 - 6911
反应条件
in methanol P=760 Torr; 20 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 39, # 51 p. 9461 - 9464
反应条件
1: 58 percent 2: 69 percent / t-BuOOLi 3: 28 percent / MgBr2*OEt2, tetra-n-butylammonium borohydride / diethyl ether; CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 3359 - 3363
