O,alpha-二甲基-DL-酪氨酸合成路线 （共 10 条）
反应条件
sodium periodate; sodium dichromate; sulfuric acid in water T=20°C; 20 h;
参考文献
Dietz, Friedrich R.; Prechter, Agnes; Groeger, Harald; Heinrich, Markus R.
Tetrahedron Letters, 2011 , vol. 52, # 6 p. 655 - 657
反应条件
barium dihydroxide in water T=125°C; 24 h;
参考文献
Obrecht; Spiegler; Schonholzer; Muller; Heimgartner; Stierli
Helvetica Chimica Acta, 1992 , vol. 75, # 5 p. 1666 - 1696
反应条件
1: 92 percent / K2CO3, KOH / benzyl triethylammonium chloride / acetonitrile / 14 h / Ambient temperature 2: 1.) hydrochloric acid (1N); 2.) hydrochloric acid (6N) / 1.) ether, 12 h, room temp.; 2.) reflux, 4 h View Scheme
参考文献
Tetrahedron, , vol. 44, # 17 p. 5343 - 5354
反应条件
1: hydrogenchloride; water; zinc / methanol / 20 °C / Reflux 2: sodium periodate; sodium dichromate; sulfuric acid / water / 20 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 6 p. 655 - 657
反应条件
1: iron sulphate heptahydrate / water; dimethyl sulfoxide / Inert atmosphere 2: hydrogenchloride; water; zinc / methanol / 20 °C / Reflux 3: sodium periodate; sodium dichromate; sulfuric acid / water / 20 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 6 p. 655 - 657
反应条件
1: 93 percent / (NH4)2CO3 / ethanol; H2O / 18 h / 80 °C 2: 91 percent / Ba(OH)2 / H2O / 24 h / 125 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 75, # 5 p. 1666 - 1696
反应条件
1: 1) LiN(SiMe3)2 / 1) THF, -76 deg C, 20 min, 2) -76 deg C to RT, overnight 2: 77 percent / HOAc, conc. aq. HCl / 2 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 7 p. 785 - 800
反应条件
thionyl chloride T=-10 - 20°C; Reflux;
参考文献
Dietz, Friedrich R.; Prechter, Agnes; Groeger, Harald; Heinrich, Markus R.
Tetrahedron Letters, 2011 , vol. 52, # 6 p. 655 - 657
参考文献
Blank; Rice; Pfeiffer; Greenberg
Journal of medicinal chemistry, 1966 , vol. 9, # 1 p. 10 - 15
反应条件
1: aq. HI
2: ICl, aq. HCl
View Scheme
参考文献
Blank; Rice; Pfeiffer; Greenberg
Journal of medicinal chemistry, 1966 , vol. 9, # 1 p. 10 - 15
