6-氯-1-1H-吲唑-3-醇合成路线 （共 4 条）
反应条件
1: 1.) aq. HCl, NaNO2, 2.) Na2SO3 / 1.) <10 deg C, 30 min, 2.) H2O, RT, 2 h 2: conc. HCl / a) RT, overnight, b) 80 deg C, 6 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 6 p. 768 - 772
反应条件
hydrogenchloride a) RT, overnight, b) 80 deg C, 6 h; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 6 p. 768 - 772
反应条件
pyridine
2 h; Heating;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 73 percent / pyridine / 2 h / Heating
2: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
3: 27 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
