N-(2-(1H-吡咯-1-基)乙基)乙酰胺合成路线 （共 10 条）
反应条件
1: 95 percent / POCl3 / 1 h / 20 °C / Heating 2: 84 percent / NaBH4 / methanol; H2O / 10 h View Scheme
参考文献
Jirkovsky, Ivo; Baudy, Reinhardt
Synthesis, 1981 , # 6 p. 481 - 483
反应条件
potassium hydroxide 2 h; Heating;
参考文献
Pleus, Susanne; Schwientek, Marion
Synthetic Communications, 1997 , vol. 27, # 17 p. 2917 - 2930
参考文献
Ciba-Geigy Corp.
Patent: US4897399 A1, 1990 ;
反应条件
acetic acid in 1,4-dioxane
Condensation;
参考文献
Pleus, Susanne; Schwientek, Marion
Synthetic Communications, 1997 , vol. 27, # 17 p. 2917 - 2930
反应条件
in 1,4-dioxane
1.) 4h, reflux, 2.) room temp., overnight;
参考文献
Jirkovsky, Ivo; Baudy, Reinhardt
Synthesis, 1981 , # 6 p. 481 - 483
反应条件
acetic acid
2 h; Reflux;
参考文献
GRUeNENTHAL GMBH; MERLA, Beatrix; OBERBOeRSCH, Stefan; REICH, Melanie; SCHUNK, Stefan; JOSTOCK, Ruth; HEES, Sabine; ENGELS, Michael; GERMANN, Tieno; BIJSTERVELD, Edward
Patent: WO2010/99938 A1, 2010 ;
Location in patent: Page/Page column 75-76 ;
反应条件
1: 95 percent / POCl3 / 1 h / 20 °C / Heating
2: 71 percent / ethanol / 15 h / Heating
3: 57 percent / NaBH4 / methanol; H2O / 2 h
View Scheme
参考文献
Jirkovsky, Ivo; Baudy, Reinhardt
Synthesis, 1981 , # 6 p. 481 - 483
反应条件
1: 65 percent / KOH aq. / 2 h / Heating
2: 63 percent / acetic acid / 48 h / Ambient temperature
View Scheme
参考文献
Jirkovsky, Ivo; Baudy, Reinhardt
Synthesis, 1981 , # 6 p. 481 - 483
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
Heating;
参考文献
Jirkovsky, Ivo; Baudy, Reinhardt
Synthesis, 1981 , # 6 p. 481 - 483
反应条件
trichlorophosphate
T=20°C; 1 h; Heating;
参考文献
Jirkovsky, Ivo; Baudy, Reinhardt
Synthesis, 1981 , # 6 p. 481 - 483
